CD117/c-kit

CD117/c-kit is a 145kDa protein found in follicular and papillary thyroid carcinoma, endometrioma, lung cancer, ovarian cancer, pancreatic cancer, breast adenocarcinoma, malignant melanoma, endothelial sinus tumor, and small cell carcinoma. The antibody can be used to differentiate gastrointestinal stromal tumors from Kaposi sarcoma, smooth muscle tumors, fibromatosis, and gastrointestinal nerve tumors, as well as to identify medulloblastomas in bone marrow.