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Actin, Muscle Specific (MSA)

MSA (muscle-specific actin), a microfilament protein with contractile capacity, is a major component of the highly conserved cytoskeleton. MSA is
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Actin, Smooth Muscle (SMA)

Antibody recognizes the α-smooth muscle isoform of actin. It shows no cross reaction with actin from fibroblasts (β and γ-cytoplasmic),
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ALK

ALK is a tyrosine kinase receptor in a large family of insulin receptors that is normally expressed at low levels
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Alpha-1-Fetoprotein (AFP)

Alpha-1-Fetoprotein is a peptide protein associated with tumor cells. It is mainly synthesized by fetal liver, but its expression is
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Androgen Receptor (AR)

AR, a member of the large family of steroid receptors, is required for the growth of prostate cancer cells and
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Bcl-2

The Bcl-2 family is the most characterized protein family involved in the regulation of apoptotic cell death and consists of
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Bcl-6

Bcl-6, a Kruppel-type zinc finger protein with a molecular weight of 96kDa, plays a role in the activation and proliferation
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c-erbB-2/HER2

c-erbB-2/HER2 is a transmembrane protein with a molecular weight of 185kDa. It is a member of the large family of
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Calcitonin (CT)

Calcitonin is a polypeptide hormone involved in calcium and phosphorus metabolism. This antibody can be used in the determination of
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Caldesmon

Caldesmon is a smooth muscle regulatory protein that can interact with actin, myosin, tropomyosin, and calmodulin, and can be used
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Calponin

Calponin is an actin filament-associated regulatory protein that interacts with actin, tropomyosin and calmodulin and participates in the smooth muscle
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Calretinin (CR)

Calretinin(CR) is a calcium-binding protein active in the cell cycle. This antibody can be used to distinguish lung adenocarcinoma from
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Carcinoembryonic Antigen (CEA)

CEA, a 180KDa glycoprotein, is mainly expressed in the epithelial tissue of fetal digestive tract, but only a small amount
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Catenin (beta)

Catenin (beta) is a protein with a molecular weight of about 92kDa. Its dysregulation of beta-catenin occurs in synovial sarcoma,
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CD10

CD10 is a common, acute lymphoblastic leukemia antigen, able to cleave and inactivate a variety of peptide growth factors that
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CD117/c-kit

CD117/c-kit is a 145kDa protein found in follicular and papillary thyroid carcinoma, endometrioma, lung cancer, ovarian cancer, pancreatic cancer, breast
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CD138

CD138 is a transmembrane glycoprotein expressed in different stages of normally differentiated lymphocytes, including pre-B cells, immature B cells, plasma
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CD19

CD19 is a mature B-cell surface glycoprotein that regulates B-cell signaling by binding to receptors and proteins and is present
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CD1a

CD1a antibody can be used to identify Langerhans cell histiocytosis, T lymphoblastic lymphoma, and leukemia.
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CD20

CD20 is a transmembrane protein of late B cell precursor and mature B cells, which plays an important role in
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CD21

CD21 is a membrane protein on B lymphocytes and is absent on T lymphocytes, monocytes, and granulocytes. This antibody can
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CD23

CD23, a 45-to 60-kda membrane glycoprotein identified as a low-affinity receptor for IgE production and a lymphocyte growth factor receptor,
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CD3

CD3 is a protein complex that binds directly to the T-cell antigen receptor. This antibody is considered a PAN-T cell
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CD30/Ki-1

CD30 is a 105/120 kda single-chain glycoprotein expressed by mononuclear Hodgkin and multinucleated R-S cells in Hodgkin’s disease. This antibody
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CD31

CD31 is a transmembrane glycoprotein member of the immunoglobulin superfamily of adhesion molecules expressed by stem cells of the hematopoietic
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CD34

CD34 is a 90-120 kda single-chain, transmembraneous, heavily glycosylated protein. The antibody can be used to identify multipotent hematopoietic stem
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CD38

CD38, a 45-kda type II membrane glycoprotein with a transmembrane sequence near the NH2 terminus, is present on early and
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CD43

CD43 is a cell surface glycoprotein expressed on both thymocytes and T cells, with an expression rate of 70.90% in
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CD45/LCA

CD45 is a transmembrane glycoprotein that is widely expressed in hematopoietic cells functioning as a tyrosine phosphatase. This antibody can
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CD5

CD5 is a cluster differentiation antigen located on T lymphocytes and some B lymphocytes. This antibody is a pan-T-cell marker
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CD56

CD56 is a cell adhesion molecule. This antibody plays an important role in the diagnosis of lymph node and nasal
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CD68

CD68, a 110kDa glycoprotein, is an important marker for the identification of macrophages. This antibody can be used to stain
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CD79a

CD79a antibody can be used to identify most precursor B-cell acute leukemias, B-cell lymphomas, and some myelomas, and is often
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CD99

CD99 is a 27 to 32 kDa glycoprotein, also known as the MIC2 gene product or E2 antigen, expressed on
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CDX-2

CDX2 is a gut-specific transcription factor that can regulate the proliferation and differentiation of intestinal epithelial cells.The antibody is mainly
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Chromogranin A (CgA)

CgA, a 68-75 kda protein, is the most abundant soluble acidic protein in the human adrenal medulla. It is widely
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COX-2

COX-2 cyclooxygenase is a key enzyme in the conversion of arachidonic acid to prostaglandin. It is expressed to varying degrees
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Cyclin D1

Cyclin D1 belongs to the cyclin D family and is one of the important cell cycle regulators. It is overexpressed
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Cytokeratin, HMW (HCK)

HCK is a high molecular weight cytokeratin that is expressed in normal squamous epithelium, ductal epithelium and other stratified epithelia.
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Cytokeratin, LMW (LCK)

LCK is a low-molecular-weight keratin that is expressed in almost all non-squamous epithelia, especially in a variety of single-layer tubular
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Cytokeratin, Pan (CK Pan)

CK Pan antibody binds to keratinized epithelium, stratified squamous epithelium, stratified epithelium, proliferating keratinized cells, and monolayer epithelia. It is
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Cytokeratin18 (CK18)

CK18 is a low molecular weight keratin with a molecular weight of 45KDa. CK18 is ubiquitously expressed in monolayer and
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Cytokeratin19 (CK19)

CK19 is a low molecular weight keratin with a molecular weight of 40KDa. CK19 is present in normal epithelium and
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Cytokeratin20 (CK20)

CK20 is a low molecular weight keratin with a molecular weight of 46KDa. CK20 is mainly expressed in the gastrointestinal
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Cytokeratin5/6 (CK5/6)

CK5/6 is a cytokeratin with a molecular weight of 58 kDa and 56 kDa, mainly expressed in the spinous layer
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Cytokeratin7 (CK7)

CK7 is a basic cytokeratin with a molecular weight of 54kDa that is present in glandular and transitional epithelial cells
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Cytokeratin8 (CK8)

CK8 is a 52.5KDa high molecular weight B-type cell keratin. In normal tissues, CK8 is expressed in almost all non-squamous
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Cytokeratin8/18 (CK8/18)

CK8/18 is a low molecular weight keratin with a molecular weight of 50/43 kDa that is expressed in all monolayer
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D2-40

D2-40 is a 40KDa glycoprotein expressed on the surface of spermatogenic cells, germ cell tumors, lymphatic endothelial cells and testicular
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Desmin

Desmin is an intermediate filament protein with a molecular weight of 53kDa, normally distributed in smooth muscle cells, cardiomyocytes, skeletal
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DOG-1

DOG-1 is a protein of unknown function. At present, it is mainly used in the diagnosis of gastrointestinal stromal tumors,
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E-Cadherin

E-cadherin, a 120kDa transmembrane glycoprotein, is a major calcium-dependent cell adhesion molecule of epithelial cells. It participates in the regulation
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EGFR

EGFR is a membrane protein with a molecular weight of 170 kDa that is widely distributed in many normal and
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Epithelial Membrane Antigen (EMA)

EMA, a 400kDa transmembrane glycoprotein, is widely distributed in the membrane of various epithelial cells and is widely used to
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Estrogen Receptor (ER)

ER is a 66kDa protein that is an important regulator of mammary gland growth and differentiation. ER is present in
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Follicle Stimulating Hormone (FSH)

FSH is a hormone secreted by anterior pituitary cells, which has the function of promoting follicle maturation and estrogen secretion.
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Galectin-3

Galectin-3, with a molecular weight of 30KDa, is a member of the β-galectin-binding family. It is expressed in the nucleus,
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GATA3

GATA3, a member of the GATA family of transcription factors, is a highly specific marker of breast and bladder related
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GFAP

GFAP is an intermediate filament protein with a molecular weight of 51kDa. It is present in astrocytes of brain tissue
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HBcAg

Hepatitis B core antigen (HBcAg) is mainly used in the determination of hepatitis, liver cirrhosis and liver cancer.
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HBsAg

Hepatitis B surface antigen (HBsAg) is mainly used in the determination of hepatitis, cirrhosis and liver cancer.
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HCG-beta

Human chorionic gonadotropin (HCG) is a glycoprotein hormone secreted by the syncytiotrophoblast cells of pregnant embryos. It belongs to the
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Helicobacter phlori (HP)

Helicobacter pylori (HP) is one of the causes of chronic gastritis and peptic ulcer in humans. It is also related
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Human Growth Hormone (hGH)

hGH, a 21.7KDa hydrophilic globulin, is a protein hormone synthesized by the anterior pituitary gland. It is mainly used in
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Human Placental Lactogen(hPL)

hPL is a polypeptide hormone synthesized by placental syncytiotrophoblastic cells. It is mainly used in the diagnosis of choriocarcinoma, testicular
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Inhibin, Alpha

Inhibin, Alpha is a glycoprotein hormone composed of alpha and beta subunits. It is expressed in the granulosa cells of
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Ki-67

Ki-67 antigen is a nuclear antigen specifically related to cell proliferation, used for cell proliferation activity determination. It is expressed
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Mammaglobin

Mammaglobin is a breast associated glycoprotein, specifically expressed in breast and in salivary gland tissues, but not in lungs related
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MART-1/Melan-A

MART-1/Melan-A is a melanocyte differentiation antigen with a molecular weight of 20kDa, which is expressed in melanocytes and malignant tumors
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Melanoma (HMB45)

HMB45 is a melanoma-associated antigen expressed in fetal and neonatal melanocytes, junctional nevus cells, blue nevus cells and malignant melanocytes.
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Mesothelial Cell (MC)

MC is mainly distributed in mesothelial cells, and generally not expressed in other glandular epithelia. MC is expressed in both
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MLH1

MLH1 is a mismatch repair protein playing an important role in maintaining the integrity and stability of genetic information and
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MSH2

MSH2 gene expression occurs in sporadic colorectal cancers. MSH2 gene mutations are associated with approximately 50% of familial and non-familial
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MSH6

MSH6 is a mismatch repair protein, frequently expressed in patients with microsatellite instability of high frequency (MSI-H), condition related to
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MUC-1

MUC1 is a member of the mucin family, and its synthesis and secretion is one of the characteristics of glandular
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MUC-2

MUC-2, a member of the mucin family, associated predominantly with digestive tract tumors. It is widely distributed in normal intestinal
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Mucin 5AC (MUC5AC)

MUC5AC, also known as gastric mucus, is mainly expressed in normal gastrointestinal epithelium, but also in colon cancer, precancerous lesions
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MUM1

MUM1, multiple myeloma oncoprotein, is a lymphoid-specific transcription factor encoded by MUM1 gene and a member of the interferon regulatory
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Myeloperoxidase (MPO)

Myeloperoxidase (MPO) is an important enzyme in granulocytes involved in the process of phagocytose and lysis of foreign bodies. MPO
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MyoD1

MyoD1, a tropomyosin-binding protein, is a marker of rhabdomyosarcoma and is mainly used for the diagnosis of rhabdomyosarcoma. A few
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Myogenin

Both Myogenin and MyoD1 are specific markers for rhabdomyosarcoma, both will mainly stain dedifferentiated tumor cells and are used for
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Napsin A

Napsin A is a single-chain protein with a molecular weight of about 38kDa. It is highly expressed in normal lungs
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Neurofilament (NF)

NF neurofilament protein is a neuron-specific intermediate filament protein composed of three subunits. It is expressed in neurons, axons, neuroblastoma,
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Neuron Specific Enolase (NSE)

NSE is a 45kDa cytoplasmic protein with three subunits, alpha, beta and gamma. The gamma subunit is mainly distributed in
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nm23

The product encoded by nm23 gene has the function of inhibiting tumor metastasis. The expression level of nm23 is high
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p120

p120, connexin, a tyrosine kinase related to E-cadherin, is expressed in invasive lobular carcinoma of the breast, gastric cancer, and
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p16

p16, also known as the “mitotic suppressor,” is one of the cell cycle regulatory proteins. The overexpression of p16 indicates
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p40

p40 is one of the isoforms of p63 protein, widely used in the classification of lung cancers. It shows a
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p504s/AMACR

p504s/AMACR is expressed in prostate adenocarcinoma, but not in benign prostate tissues. P504s/AMACR is also expressed in precancerous lesions of
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p53

p53 is a phosphoprotein, tumor suppressor, with a molecular weight of 53Kda. It has two forms: wild type and mutant
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p63

p63 is a marker of prostatic basal cells, but it is not expressed in the vast majority of prostate tumors.
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Pax-8

Pax-8 is a 48KDa protein highly expressed in malignant tumors of ovarian origin. Combined with TTF-1, it can be used
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PD-1

PD-1 (programmed death 1) is a negative costimulatory molecule and a new marker for the diagnosis of angioimmunoblastic T-cell lymphoma
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PD-L1

PD-L1, also known as surface antigen differentiation cluster 274 (CD274), is a type I transmembrane protein with a molecular weight
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Perforin

Perforin is a substance produced in cytotoxic T lymphocytes, causing water to enter the cytoplasm leading to target cell lysis/apoptosis.
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Placental Alk Phosphatase (PLAP)

PLAP is a membrane-bound alkaline phosphatase with a molecular weight of 70KDa, present in normal placenta. It is also expressed
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PMS2

PMS2 is a 96kDa mismatch repair protein, mainly involved to correct single base mismatch and small fragment mismatch disorders. Defects
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Progesterone Receptor (PR)

PR is an estrogen regulatory protein with two isoforms, PGRα and PGRβ, with molecular weight of 94KDa and 114KDa, respectively.
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Prostate Specific Acid Phosphatase (PSAP)

PSAP is a 52kDa prostatic acid phosphatase expressed in normal prostate tissue, hyperplastic prostate tissue and prostate cancer. It is
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Prostate Specific Antigen (PSA)

PSA is a glycoprotein synthesized by prostate epithelial cells with a molecular weight of 33kDa. Protein is present in normal
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PTEN

PTEN gene, also known as MMAC1 or TEP1, is a tumor suppressor gene located on human chromosome 10q23. Its expression
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S-100 Protein

S-100 is a soluble acidic protein with a molecular weight of 21-24 kda, expressed in nervous system tissues, pituitary gland,
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Surfactant Protein B (SP-B)

SP-B is a surfactant protein secreted by lung’s type Ⅱ alveolar epithelial cells. It is expressed in normal lung type
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Surfactant Protein-A (SP-A)

Surfactant Protein A (SP-A) is located in type II alveolar epithelial cells of lungs and plays an important role in
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Survivin

Survivin is a member of the apoptosis inhibitor gene family, mainly expressed in the G2/M phase of the cell cycle.
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Synaptophysin (Syn)

Synaptophysin is a 38-kDa transmembrane glycoprotein located in presynaptic vesicles and expressed in the presynaptic central and peripheral nervous system,
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Terminal Deoxyribonucleotidyl Transferase (TdT)

TdT is a nuclear polymerase expressed in normal thymic cortical cells and blast lymphocytes but not in mature T or
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Thyroglobulin (TG)

TG thyroglobulin is a 330KDa glycoprotein expressed in thyroid follicular epithelium and glia, all thyroid follicular tumors, thyroid papillary carcinoma,
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Thyroid Peroxidase (TPO)

Thyroid peroxidase (TPO) is located on the apical free surface of thyroid epithelial cells. It is directly involved in the
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Thyroid Stimulating Hormone (TSH)

TSH is a glycoprotein secreted by the eosinophilic cells of the adenohypophysis and stimulates the secretion of thyroxine. It is
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Thyroid TranscriptionFactor-1 (TTF-1)

TTF-1 is a 40kDa thyroid transcription factor expressed in thyroid and lung epithelial cells. TTF-1 was expressed in most small
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Topoisomerase II alpha (TOP2A)

TOP2A is a member of the topoisomerase family of proteins with a molecular weight of 170kDa. It plays an important
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Vascular Endothelial Growth Factor (VEGF)

VEGF is a protein with a molecular weight of 34-50 kda. VEGF and its receptor are recognized as the key
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Villin

Villin is a 95KDa cytoskeletal protein normally expressed in the intestinal epithelium and renal proximal tubular epithelium. It can be
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Vimentin

Vimentin, an intermediate filament protein with a molecular weight of 57KDa, is the most widely distributed intermediate filament, expressed in
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Wilm’s Tumor (WT1)

Antiboby targets epitope expressed in Wilms tumor, fetal and adult kidney, developing ovary, and testis, but not in endometrial, cervical
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